Cost has largely replaced distance as the measure of how hard it is to get around. Sure, Indianapolis is closer to Philadelphia than Chicago, but the price of airline tickets is unlikely to reflect that geography.
In order to better understand the domestic travel landscape, the Research and Innovative Technology Administration's Bureau of Transportation Statistics undertook a study to find which American airports are the most expensive to fly out of, as measured by ticket value, taxes and fees. The results are interesting and indicative of how smaller markets are often less served by the modern aviation industry than hubs -- though overcharged fliers may want to skip Newark-Liberty and head to Atlantic City instead.
The priciets, beginning with Cleveland's Hopkins Airport at number 10, are part of a club with high membership fees and no perks at all. Sorry C-Towners. At least Hopkins isn't one of the most dangerous airports or one of the busiest.